A guy with an unsatisfactory job, fake friends, and an awful girlfriend is hit by a car. He survives the accident and awakens in his hospital room while the Doctor and his girlfriend are outside discussing his situation, a conversation that he can overhear. The Doctor mentions that our main character might suffer temporary amnesia. The man takes advantage of this fact, and uses the opportunity to recreate his life from the ground up (quitting job for better one, breaking up with gf, etc..) Throw in a love interest and I think it would made a decent movie.
This sounds like a great vehicle for Charlie Day