I actually like the style of humor that CB!B! goes for to be honest. The issue lies from a random episode I listened to one night at work with Patton Oswalt and I really didn't care for the premise of the episode so I ended up not listening to any more episodes from that point. However, I recently watched the CB!B! show on Netflix and really enjoyed it so I'm willing to give it another shot based on the enjoyment I got from the show.
Oh, well in that case, if one episode's style turned you away, you shouldn't have any trouble recovering from that issue at all. Each episode goes in such a drastically different from the last based solely on the guest/game played. I actually think I know which one you're referring to, because Patton hasn't been part of any great episodes, surprisingly enough.